Cystic Fibrosis

New paper on “Evaluation of automated airway morphological quantification for assessing fibrosing lung disease” to be presented at Deep Generative Models workshop @ MICCAI 2022. We present a completely labelless automated airway measurement method that learns to regress to an airway’s diameter.

The problem Chronic lung diseases, like idiopathic pulmonary fibrosis (IPF) are characterised by abnormal dilatation of the airways. Quantification of airway features on computed tomography (CT) can help characterise disease progression.

BMVA April 2022 Symposium - Abstract Download Poster Abnormal airway dilation, termed bronchiectasis, is a feature of many chronic airway diseases. It is identified qualitatively on computed tomography (CT) in the clinic; however, quantitative analysis would make measurements of disease severity more precise and objective.

• On computed tomographic imaging, bronchiectasis appearances and distribution within the lung can suggest the underlying disease cause …

The goal of this project is to come up with a more objective method to measure the severity of structural lung diseases such as cystic fibrosis and idiopathic pulmonary fibrosis. In these diseases, the airways dilate and worsen with disease progression (bronchiectasis).